Formal Statement on the Mechanism of Action of “Morgellons” by Don Mau. submitted to the CDC's vector borne disease unit in Fort Collins, Colorado on 12/8/2016

A fibroblast is a type of cell that synthesizes the extracellular matrix and collagen. Fibroblasts are involved in tissue repair during an injury, they activate platelets which then release chemical signals called “Growth Factors”. FGF or Fibroblast Growth Factor then stimulates Fibroblasts by linking with receptors on the cell surface generating proteins for cell growth and tissue repair. In other words the FGF delivers a chemical signal to the cell receptor telling the cell how to perform.

If there is an induced gene mutation in either the FGF or the receptor then the information delivered to the cell will cause mutated results.

Bartonella infection causes changes in multiple growth factors including FGF.

https://www.ncbi.nlm.nih.gov/pubmed/?term=bartonella+fgf

[Infection and angiomatous cutaneous lesions]

“these are associated with multifocal tumorous proliferations (of endothelial and fusiform cells) affected by angiogenic growth factors (PDGF, FGF, IL6, alphaTGF, HIVtat, androgens”

Bacteria normally use Horizontal Gene Transfer or Lateral Gene Transfer among themselves, Prokaryotic Cells without a nucleus are bacteria. Human cells or eukaryotic cells that have a nucleus can not normally have their DNA altered  by bacteria. However there two bacteria known to science that can insert DNA into human cells. One of these bacteria is Agrobacterium and is used to GM the food supply because of that ability. The only other Bacteria known to science that can accomplish the insertion of DNA into our cells is Bartonella which is closely related to Agrobacteria and also has the T4SS needed for HGT
http://www.pnas.org/content/108/35/14643.abstract

“Conjugative DNA transfer into human cells by the VirB/VirD4 type IV secretion system of the bacterial pathogen Bartonella henselae”

“Bacterial type IV secretion systems (T4SS) mediate interbacterial conjugative DNA transfer and transkingdom protein transfer into eukaryotic host cells in bacterial pathogenesis. The sole bacterium known to naturally transfer DNA into eukaryotic host cells via a T4SS is the plant pathogen Agrobacterium tumefaciens. Here we demonstrate T4SS-mediated DNA transfer from a human bacterial pathogen into human cells. We show that the zoonotic pathogen Bartonella henselae can transfer a cryptic plasmid occurring in the bartonellae into the human endothelial cell line EA.hy926 via its T4SS VirB/VirD4”

Fiber production is a symptom of Bartonellosis caused by a gene mutation induced by the infection. The fibers have shown numerous times to be composed of Collagen and Keratin and these are the proteins that fibroblasts create.

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https://f1000research.com/articles/2-118/v1

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"identifying the filaments found in MD as keratin and collagen based and furthermore associated with spirochetal infection."  The spirochetal association makes sense put into the following context.

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http://www.townsendletter.com/July2009/ed_lyme0709.html
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“The knowledge base about both Bartonella testing and treatment borders on the disastrous. Bartonella is one of the most common infections in the world. Calling it a "coinfection" is nonsense; if anything, Lyme is the "coinfection." It is found in vast numbers of common vectors, including dust mites, fleas, flea feces, pet saliva, and ticks. Amazingly, it can turn off or lower antibodies to Lyme disease, Babesia, Ehrlichia, Anaplasma, and even itself. Bartonella floats in blood and also enters all blood vessel walls without causing a fatal fever, and indeed actually lowers fevers. It is the ultimate stealth infection. It turns off antibodies, fevers, and immune function defense chemicals as it damages organs in 20 to 60 ways.”
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https://www.ncbi.nlm.nih.gov/pubmed/12397374

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"Crucial role of fibroblasts in regulating epidermal morphogenesis"

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Since Bartonella can receive DNA from other  bacteria and evolve it's abilities in this way then it should be noted that it is special in it's ability to also be able to transfer DNA into humans and it is possible that acquired DNA has upgraded a strain of Bartonella to become the "Morgellons" pathogen. 

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012666

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"Evidence of Transfer by Conjugation of Type IV Secretion System Genes between Bartonella Species and Rhizobium radiobacter in Amoeba"

"Conclusions
Based on this, we speculate that amoeba favor the transfer of genes as phagocytic protists, which allows for intraphagocytic survival and, as a consequence, promotes the creation of potential pathogenic organisms."


https://www.ncbi.nlm.nih.gov/pubmed/11260140

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"Formation of stress fibres in human endothelial cells infected with Bartonella bacilliformis is associated with altered morphology, impaired migration and defects in cell morphogenesis"

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https://en.wikipedia.org/wiki/Actin

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"A large number of illnesses and diseases are caused by mutations in alleles of the genes that regulate the production of actin or of its associated proteins. The production of actin is also key to the process of infection by some pathogenic microorganisms."


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Update 12/13/2016 the CDC has acknowledged receipt of this info  [ ref:_00DU0YCBU._500t04NWIU:ref ]

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Don Mau

www.lyme-morgellons.com

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https://www.facebook.com/nbprotocol/

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PLEASE SIGN MY PETITION

https://www.change.org/p/cdc-director-dr-tom-frieden-cdc-reopen-the-investigation-into-morgellons